Dostinex is used for treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. Dostinex is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.
Use Dostinex as directed by your doctor.
- Take Dostinex by mouth with or without food.
- It may be helpful to mark on a calendar which days you are supposed to take Dostinex.
- If you miss a dose of Dostinex, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Dostinex.
Store Dostinex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dostinex out of the reach of children and away from pets.
Active Ingredient: Cabergoline.
Do NOT use Dostinex if:
- you are allergic to any ingredient in Dostinex or to ergot derivatives (eg, ergotamine)
- you have uncontrolled high blood pressure
- if you have a history of certain fibrotic (scarring) disorders (eg, of the lung, heart, kidneys)
- you are taking a butyrophenone (eg, haloperidol), metoclopramide, a phenothiazine (eg, chlorpromazine), or a thioxanthene (eg, thiothixene).
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Dostinex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver problems or high blood pressure, or if you take medicine that may lower your blood pressure
- if you have certain serious problems cause by pregnancy (eg, high blood pressure, seizures).
Some medicines may interact with Dostinex. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Macrolides (eg, clarithromycin) because they may increase the risk of Dostinex's side effects
- Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Dostinex's effectiveness.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dostinex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Dostinex may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Dostinex with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
- Dostinex may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Some patients taking Dostinex have developed certain behavioral changes (eg, increased gambling or sexual urges). These effects usually go away when treatment with Dostinex is stopped. Contact your doctor right away if you notice any unusual behavioral changes.
- If you think you may be pregnant, contact your doctor so that a pregnancy test can be arranged.
- Lab tests, including heart function, may be performed while you use Dostinex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Dostinex should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dostinex while you are pregnant. It is not known if Dostinex is found in breast milk. Do not breast-feed while taking Dostinex.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Constipation; dizziness; headache; indigestion; nausea; tiredness or weakness; vomiting.